HA-155

Modify Date: 2024-01-08 10:30:08

HA-155 Structure
HA-155 structure
Common Name HA-155
CAS Number 1229652-22-5 Molecular Weight 463.29
Density 1.4±0.1 g/cm3 Boiling Point 691.0±65.0 °C at 760 mmHg
Molecular Formula C24H19BFNO5S Melting Point N/A
MSDS N/A Flash Point 371.7±34.3 °C

 Use of HA-155


(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].

 Names

Name HA-155
Synonym More Synonyms

 HA-155 Biological Activity

Description (E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].
Related Catalog
Target

Autotaxin[1]

References

[1]. Joncour A, et al. Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors [published correction appears in J Med Chem. 2018 May 10;61(9):4270]. J Med Chem. 2017;60(17):7371-7392.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 691.0±65.0 °C at 760 mmHg
Molecular Formula C24H19BFNO5S
Molecular Weight 463.29
Flash Point 371.7±34.3 °C
Exact Mass 463.106110
LogP 5.25
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.683

 Synonyms

{4-[(4-{(Z)-[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acid
MFCD28016544
HA-155
Boronic acid, B-[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-
HA-130
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