1355026-47-9

1355026-47-9 structure

Name: CYM50179
Chemical Name: ML-178
CAS Number: 1355026-47-9
Molecular Formula: C₁₃H₉Br₂Cl₂NO₂
Molecular Weight: 441.93
Catalog: Signaling Pathways GPCR/G Protein LPL Receptor
Create Date: 2021-05-05 18:58:45
Modify Date: 2024-01-20 14:50:38
CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].

Name	ML-178
Synonyms	2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]pyridine Pyridine, 2,6-dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]- ML-178

Description	CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> LPL Receptor Research Areas >> Inflammation/Immunology
Target	S1PR4:46 nM (EC50)
References	[1]. Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42.