208445-06-1

208445-06-1 structure

Name: Rp-8-Br-cGMPS
Chemical Name: Rp-8-bromo-Cyclic GMPS (sodium salt)
CAS Number: 208445-06-1
Molecular Formula: C₁₀H₁₀BrN₅NaO₆PS
Molecular Weight: 462.15
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2021-05-12 16:03:53
Modify Date: 2024-07-19 12:10:42
Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1].

Name	Rp-8-bromo-Cyclic GMPS (sodium salt)
Synonyms	Sodium (2R,4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2-thiolate 2-oxide Rp-8-Bromoguanosine- 3', 5'- cyclic monophosphorothioate sodium salt Sodium (2R,4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide Rp-8-Br-Cgmps Sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(2R,4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-sulfido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) Rp-8-Br-cGMPS sodium salt MFCD04037242 Rp-8-Bromo-cGMPS sodium salt Rp-8-bromo-Cyclic GMPS (sodium salt) 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(2R,4aR,6R,7R,7aS)-tetrahydro-7-hydroxy-2-mercapto-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-sulfido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-7-hydroxy-2-mercapto-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) Sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2-thiolate 2-oxide

Description	Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Metabolic Disease
References	[1]. Rashatwar SS, et, al. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5685-9.

Molecular Formula	C₁₀H₁₀BrN₅NaO₆PS
Molecular Weight	462.15
Exact Mass	460.917053

150418-07-8	208445-06-1
185246-32-6	172806-20-1
153660-03-8	129735-00-8
788807-32-9	208445-07-2
276696-61-8	153660-04-9
1158522-08-7	940364-43-2
134104-43-1	131615-57-1
6906-52-1	2138199-34-3
930439-75-1	1018584-77-4
1375289-11-4	849349-65-1