Rp-8-Br-cGMPS

Modify Date: 2024-07-19 12:10:42

Rp-8-Br-cGMPS Structure
Rp-8-Br-cGMPS structure
Common Name Rp-8-Br-cGMPS
CAS Number 208445-06-1 Molecular Weight 462.15
Density N/A Boiling Point N/A
Molecular Formula C10H10BrN5NaO6PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Rp-8-Br-cGMPS


Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1].

 Names

Name Rp-8-bromo-Cyclic GMPS (sodium salt)
Synonym More Synonyms

 Rp-8-Br-cGMPS Biological Activity

Description Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1].
Related Catalog
References

[1]. Rashatwar SS, et, al. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5685-9.  

 Chemical & Physical Properties

Molecular Formula C10H10BrN5NaO6PS
Molecular Weight 462.15
Exact Mass 460.917053

 Synonyms

Sodium (2R,4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2-thiolate 2-oxide
Rp-8-Bromoguanosine- 3', 5'- cyclic monophosphorothioate sodium salt
Sodium (2R,4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide
Rp-8-Br-Cgmps
Sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(2R,4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-sulfido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1)
Rp-8-Br-cGMPS sodium salt
MFCD04037242
Rp-8-Bromo-cGMPS sodium salt
Rp-8-bromo-Cyclic GMPS (sodium salt)
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(2R,4aR,6R,7R,7aS)-tetrahydro-7-hydroxy-2-mercapto-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1)
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-2,7-dihydroxy-2-sulfido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1)
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(4aR,6R,7R,7aS)-tetrahydro-7-hydroxy-2-mercapto-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1)
Sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2-thiolate 2-oxide
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