208445-07-2

208445-07-2 structure

Name: Rp-8-pCPT-cGMPS sodium
Chemical Name: Rp-8-pCPT-Cyclic GMPS (sodium salt)
CAS Number: 208445-07-2
Molecular Formula: C₁₆H₁₄ClN₅NaO₆PS₂
Molecular Weight: 525.859
Create Date: 2021-05-12 16:03:56
Modify Date: 2024-01-09 06:47:15
Rp-8-pCPT-Cyclic GMPS sodium salt is a stable, cell-permeable cGMP analog that competitively inhibits cGMP-dependent protein kinases (cGKs), including cGK Iα and cGK II (IC50s, 18.3 and 0.16 M, respectively).

Name	Rp-8-pCPT-Cyclic GMPS (sodium salt)
Synonyms	Rp-8-pCPT-Cyclic GMPS (sodium salt) 6H-Purin-6-one, 2-amino-8-[(4-chlorophenyl)thio]-1,9-dihydro-9-[(2R,4aR,6R,7R,7aS)-tetrahydro-7-hydroxy-2-mercapto-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) Sodium (2R,4aR,6R,7R,7aS)-6-{2-amino-8-[(4-chlorophenyl)sulfanyl]-6-oxo-1,6-dihydro-9H-purin-9-yl}-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2-thiolate 2-oxide