1246817-56-0
1246817-56-0 structure
- Name: Tizoxanide-d4
- Chemical Name: Tizoxanide-d4
- CAS Number: 1246817-56-0
- Molecular Formula: C10H3D4N3O4S
- Molecular Weight: 269.270
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2021-06-06 19:22:30
- Modify Date: 2024-01-02 16:29:49
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Tizoxanide D4 (TIZ D4) is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].
| Name | Tizoxanide-d4 |
|---|---|
| Synonyms |
2-Hydroxy-N-(5-nitro-1,3-thiazol-2-yl)(2H4)benzamide
Benzamide-2,3,4,5-d4, 6-hydroxy-N-(5-nitro-2-thiazolyl)- Tizoxanide-d4 |
| Description | Tizoxanide D4 (TIZ D4) is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C10H3D4N3O4S |
| Molecular Weight | 269.270 |
| Exact Mass | 269.040833 |
| LogP | 2.91 |
| Index of Refraction | 1.750 |