1770778-45-4
1770778-45-4 structure
- Name: 3,4,5-Trihydroxycinnamic acid decyl ester
- Chemical Name: 3,4,5-Trihydroxycinnamic acid decyl ester
- CAS Number: 1770778-45-4
- Molecular Formula: C19H28O5
- Molecular Weight: 336.42
- Catalog: Research Areas Metabolic Disease
- Create Date: 2021-09-10 00:10:06
- Modify Date: 2024-01-10 13:37:16
-
3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1].
| Name | 3,4,5-Trihydroxycinnamic acid decyl ester |
|---|
| Description | 3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
EC50: 0.9 μM (pancreatic lipase)[1] |
| In Vitro | 3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro[1]. 3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM[1]. 3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation[1]. |
| In Vivo | 3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally[1]. Animal Model: 6 weeks old Male ddY mice[1] Dosage: 30 mg/kg, 150 mg/kg Administration: Oral administration Result: Reduced plasma TG in a dose-dependent manner. |
| References |
| Molecular Formula | C19H28O5 |
|---|---|
| Molecular Weight | 336.42 |
| Hazard Codes | Xi |
|---|