1095003-80-7
1095003-80-7 structure
- Name: p38α inhibitor 2
- Chemical Name: p38α inhibitor 2
- CAS Number: 1095003-80-7
- Molecular Formula: C27H33N5O3
- Molecular Weight: 475.58
- Create Date: 2021-06-09 08:12:10
- Modify Date: 2024-01-22 13:53:26
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p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC50 of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC50=27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targets.
| Name | p38α inhibitor 2 |
|---|
| Description | p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC50 of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC50=27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targets. |
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| Molecular Formula | C27H33N5O3 |
|---|---|
| Molecular Weight | 475.58 |