Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Deoxycorticosterone acetate
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Deoxycorticosterone acetate
Price: ￥1198.0/1g ￥218.0/250mg ￥1898.0/5g
Purity: 99.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Deoxycorticosterone acetate
Price: $300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Deoxycorticosterone acetate
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Deoxycorticosterone acetate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

56-47-3

56-47-3 structure

Name: Deoxycorticosterone acetate
Chemical Name: 21-(acetyloxy)-pregn-4-ene-3,20-dione
CAS Number: 56-47-3
Molecular Formula: C₂₃H₃₂O₄
Molecular Weight: 372.498
Catalog: Pharmaceutical intermediate Heterocyclic compound Isoquinoline compound
Create Date: 2018-02-11 08:00:00
Modify Date: 2024-01-02 16:19:37
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.

Name	21-(acetyloxy)-pregn-4-ene-3,20-dione
Synonyms	21-Acetyloxypregn-4-ene-3,20-dione 2-[(8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethylacetat DOXO Descotone Deoxycostone Acetate 2-[(8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl acetate Pregn-4-ene-3,20-dione, 21- (acetyloxy)- 3,20-Dioxopregn-4-en-21-ylacetat Desoxycorticosterone acetate (USP) Doca Syncort [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate Acétate de 2-[(8S,9S,10R,13S,14S,17S)-10,13-diméthyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-1H-cyclopenta[a]phénanthrén-17-yl]-2-oxoéthyle 3,20-Dioxopregn-4-en-21-yl acetate MFCD00003660 EINECS 200-275-9 Pregn-4-ene-3,20-dione, 21-(acetyloxy)- Deoxycorticosterone acetate

Description	Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Mineralocorticoid Receptor Research Areas >> Endocrinology

Density	1.1±0.1 g/cm3
Boiling Point	504.1±50.0 °C at 760 mmHg
Melting Point	157°C
Molecular Formula	C₂₃H₃₂O₄
Molecular Weight	372.498
Flash Point	218.0±30.2 °C
Exact Mass	372.230072
PSA	60.44000
LogP	4.53
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.542
Storage condition	Refrigerator
Water Solubility	H2O: insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HG0525000

CHEMICAL NAME :: 11-Deoxycorticosterone, acetate

CAS REGISTRY NUMBER :: 56-47-3

BEILSTEIN REFERENCE NO. :: 2570798

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C23-H32-O4

MOLECULAR WEIGHT :: 372.55

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A F FV1OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 520 mg/kg/13W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 83,14,1953 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1258 mg/kg

SEX/DURATION :: male 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 28,129,1941

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 316 mg/kg

SEX/DURATION :: female 56 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth)

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 120,238,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 224 mg/kg

SEX/DURATION :: female 56 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 120,238,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 16 mg/kg

SEX/DURATION :: male 2 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles)

REFERENCE :: ANENAG Annales d'Endocrinologie. (Masson Editeur, 120 Blvd. Saint-Germain, F-25280 Paris Cedex 06, France) V.1- 1939- Volume(issue)/page/year: 24(Suppl 3),1,1963 *** REVIEWS *** TOXICOLOGY REVIEW CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 17,432,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5546 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 968 (estimated) No. of Female Employees: 494 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	UN 2811
WGK Germany	3
RTECS	HG0525000
Packaging Group	II
Hazard Class	6.1

Precursor 5
64-85-7 108-24-7 566-78-9 62490-13-5
1171-90-0
DownStream 7
567-02-2 298-36-2 303-01-5 111464-71-2
302-97-6 80-92-2 64-85-7

56-47-3	27863-60-1
88378-35-2	1420-82-2
2402-24-6	10147-45-2
140194-24-7	3473-63-0
6846-03-3	6380-28-5
1158522-08-7	940364-43-2
134104-43-1	131615-57-1
6906-52-1	1235690-58-0
930439-75-1	1018584-77-4
1375289-11-4	849349-65-1