Henan Tianfu Chemical Co., Ltd.
China
Product Name: Prednisone 21-acetate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

125-10-0

125-10-0 structure

Name: d-Corlin
Chemical Name: cortancyl
CAS Number: 125-10-0
Molecular Formula: C₂₃H₂₈O₆
Molecular Weight: 400.46
Catalog: API Hormone and endocrine-regulating drugs Adrenal corticosteroids
Create Date: 2018-02-07 08:00:00
Modify Date: 2026-07-01 17:26:21
Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

Name	cortancyl
Synonyms	δ-Cortelan [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate prednisone 21-acetate 21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione Prednisone acetate, Glucocorticoid MFCD00200229 Prednisone 21-acetate deltalone 21-Acetoxy-17a-hydroxypregna-1,4-diene-3,11,20-trione (Prednisone Acetate) delta-corlin EINECS 204-726-0 [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate hot selling Prednisone 21-acetate [2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate Prednisolone Impurity 32 ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER d-Cortelan Prednisone 21-acetate //BP Prednisone 21-acetate / Dehydrocortisone acetate Prendnisone acetate Prednisone 21-acetat Prednisone/ Prednisone Acetate 21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione Cortancyl (Prednisone 21-acetate) 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate 17-Hydroxy-3,11,20-trioxopregna-1,4-dien-21-yl acetate acetic acid [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] ester δ-Corlin 1-DEHYDROCORTISONE ACETATE 1-Cortisone 21-Acetate 4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate 1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate Alitretinoin Impurity 22 Prednisone acetate, 10 mM in DMSO Prednisone Impurity E (Prednisone 21-Acetate) 17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE delcortin Prednisone Impurity E acetic acid [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-3,11-diketo-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester delta’-dehydrocortisoneacetate Dehydrocortisone acetate PREDNISONE ACETATE nisone Prednisone Impurity 6 Pregna-1,4-diene-3,11,20-trione,21-(acetyloxy)-17-hydroxy 11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3 Ferr Cblconin

Description	Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
Target	glucocorticoid receptor[1]
References	[1]. Prednisolone acetate

Density	1.3±0.1 g/cm3
Boiling Point	582.0±50.0 °C at 760 mmHg
Melting Point	240-242°C (dec.)
Molecular Formula	C₂₃H₂₈O₆
Molecular Weight	400.46
Flash Point	200.2±23.6 °C
Exact Mass	400.188599
PSA	97.74000
LogP	2.66
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.580
Storage condition	Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4154085

CHEMICAL NAME :: Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate

CAS REGISTRY NUMBER :: 125-10-0

BEILSTEIN REFERENCE NO. :: 2342061

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H28-O6

MOLECULAR WEIGHT :: 400.51

WISWESSER LINE NOTATION :: L E5 B666 CV OV AHTTT&J A1 E1 FV1OV1 FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 330 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 56,23,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 135 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 56,23,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3270 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1045 (estimated) No. of Female Employees: 1045 (estimated)

Hazard Codes	Xi
Risk Phrases	R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36/37/39
HS Code	2937210000

52-21-1

~99%

125-10-0

Literature: Lapitskaya, Margarita A.; Vasiljeva, Ljudmila L.; Pivnitsky, Kasimir K. Mendeleev Communications, 2008 , vol. 18, # 6 p. 309 - 311

50-24-8

125-10-0

Literature: Journal of the American Chemical Society, , vol. 77, p. 4781,4783

28449-43-6

125-10-0

Literature: Journal of the American Chemical Society, , vol. 77, p. 4436

50-04-4

125-10-0

Literature: Helvetica Chimica Acta, , vol. 39, p. 734,741 Recueil des Travaux Chimiques des Pays-Bas, , vol. 75, p. 475,480

53-03-2

108-24-7

125-10-0

Literature: Heterocyclic Communications, , vol. 9, # 6 p. 575 - 578

52-21-1

898-84-0

125-10-0

Literature: Journal of Pharmaceutical Sciences, , vol. 72, # 1 p. 30 - 35

Precursor 6
52-21-1 50-24-8 28449-43-6 50-04-4
53-03-2 108-24-7
DownStream 3
3044-42-6 17652-24-3 53-03-2

HS Code	2937210000

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