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1165-39-5

1165-39-5 structure

Name: Aflatoxin G1
Chemical Name: Aflatoxin G1
CAS Number: 1165-39-5
Molecular Formula: C₁₇H₁₂O₇
Molecular Weight: 328.273
Catalog: analytical chemistry Standard Food and cosmetics standards
Create Date: 2018-02-19 08:00:00
Modify Date: 2026-07-01 18:33:04
Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].

Name	Aflatoxin G1
Synonyms	AFLATOXIN G1 FROM ASPERGILLUS FLAVUS AflatoxinG1Solution,3mg/L aflatoxin g1 solution Aflatoxin G1,crystalline (7,10aS)-3,4,7a,10a-Tetrahydro-5-Methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione 1h,12h-Furo[3',2':4,5]Furo[2,3-H]Pyrano[3,4-C]Benzopyran-1,12-Dione, 3,4,7a,10a-Tetrahy 5-Methoxy-3,4,7aα,10aα-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione aflatoxin g1solution Aflatoxin G1 Solution in Acetonitrile, 100μg/mL AF G1 (7-3,4,7aα,10aα-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione Aflatoxin G1 3.78μg/g in Acetonitrile 5-methoxy-3,4-dihydrofuro[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12(7aH,10aH)-dione Aflatoxin G1 2ug/ml in ACN Aflatoxin G(1) 3,4,7aα,10aα-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione Aflatoxins in Paprika Powder AFLATOXIN G EINECS 214-615-9 Aflatoxin G1, crystalline (7-cis)-10a-tetrahydro-5-methoxy AFLATOXIN G1(RG) 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7-cis) AF G1;Aflatoxin G1 5-Methoxy-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-H]pyrano[3,4-c]chromene-1,12-dione (7,cis)3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione Aflatoxin G1 (7,10aS)-3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione Aflatoxin G1 Solution in Acetonitrile, 10μg/mL 10a-tetrahydro-5-methoxy 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]benzopyran-1,12-dione,3,4,7a,10a-tetrahydro-5-methoxy-, (7,10aS) AFLATOXIN G1 MFCD00005089 AFLATOXIN G FROM ASPERGILLUS FLAVUS VIAL WITH (7ar-cis)-10a-tetrahydro-5-methoxy Aflatoxin Quality Control Sample,From wheat 1h,12h-furo(3’,2’:4,5)furo(2,3-h)pyrano(3,4-c)benzopyran-1,12-dione,3,4,7a (7aR,10aS)-5-Methoxy-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione

Description	Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Sarma UP, et al. Aflatoxins: Implications on Health. Indian J Clin Biochem. 2017 Jun;32(2):124-133. [2]. Karaaslan M, et al. Aflatoxins B1, B2, G1, and G2 contamination in ground red peppers commercialized in Sanliurfa, Turkey. Environ Monit Assess. 2015 Apr;187(4):184.

Density	1.6±0.1 g/cm3
Boiling Point	612.1±55.0 °C at 760 mmHg
Melting Point	244-246ºC
Molecular Formula	C₁₇H₁₂O₇
Molecular Weight	328.273
Flash Point	274.1±31.5 °C
Exact Mass	328.058289
PSA	84.20000
LogP	-0.17
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.680

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LV1720000

CAS REGISTRY NUMBER :: 1165-39-5

BEILSTEIN REFERENCE NO. :: 1299768

LAST UPDATED :: 199806

DATA ITEMS CITED :: 39

MOLECULAR FORMULA :: C17-H12-O7

MOLECULAR WEIGHT :: 328.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14900 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - pleural effusion Liver - jaundice, other or unclassified Endocrine - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 785 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4100 ug/kg/22W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 24 mg/kg/20W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 mg/kg/20W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5600 ug/kg/2W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: Sperm Morphology

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Primate - monkey Kidney

DOSE/DURATION :: 2 mg/L

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 48,1647,1972 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 10,51,1976 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,245,1993 TOXICOLOGY REVIEW LLOYA2 Lloydia. (Cincinnati, OH) V.1-41, 1938-78. For publisher information, see JNPRDF. Volume(issue)/page/year: 38,21,1975 TOXICOLOGY REVIEW BAREA8 Bacteriological Reviews. (Washington, DC) V.1-41, 1937-77. Volume(issue)/page/year: 30,460,1966 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974 TOXICOLOGY REVIEW IJNDAN Indian Journal of Nutrition and Dietetics. (Sri Avinashilingam Home Science College for Women, Coimbatore 641 043, India) V.7- 1970- Volume(issue)/page/year: 8,85,1971

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H304-H315-H319-H340-H350-H372
Precautionary Statements	P201-P210-P301 + P310-P305 + P351 + P338-P308 + P313-P331
Personal Protective Equipment	Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;T+: Very toxic;F: Flammable;Xn: Harmful;
Risk Phrases	R45
Safety Phrases	53-28-36/37-45-62-26-16-7-36
RIDADR	UN 3462 6
WGK Germany	3
RTECS	LV1720000
Packaging Group	I
Hazard Class	6.1(a)

1162-65-8

1165-39-5

Literature: Mutation Research, , vol. 313, # 1 p. 25 - 38

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