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1165-39-5

1165-39-5 structure
1165-39-5 structure
  • Name: Aflatoxin G1
  • Chemical Name: Aflatoxin G1
  • CAS Number: 1165-39-5
  • Molecular Formula: C17H12O7
  • Molecular Weight: 328.273
  • Catalog: analytical chemistry Standard Food and cosmetics standards
  • Create Date: 2018-02-19 08:00:00
  • Modify Date: 2024-01-02 09:07:44
  • Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].
Name Aflatoxin G1
Synonyms AF G1
MFCD00005089
Aflatoxin G(1)
1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR,10aS)-
aflatoxin g1 solution
AFLATOXIN G
EINECS 214-615-9
Aflatoxin G1,crystalline
(7ar-cis)-10a-tetrahydro-5-methoxy
10a-tetrahydro-5-methoxy
Aflatoxin G1
(7aR,10aS)-5-Methoxy-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione
Description Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].
Related Catalog
References

[1]. Sarma UP, et al. Aflatoxins: Implications on Health. Indian J Clin Biochem. 2017 Jun;32(2):124-133.

[2]. Karaaslan M, et al. Aflatoxins B1, B2, G1, and G2 contamination in ground red peppers commercialized in Sanliurfa, Turkey. Environ Monit Assess. 2015 Apr;187(4):184.
Density 1.6±0.1 g/cm3
Boiling Point 612.1±55.0 °C at 760 mmHg
Melting Point 244-246ºC
Molecular Formula C17H12O7
Molecular Weight 328.273
Flash Point 274.1±31.5 °C
Exact Mass 328.058289
PSA 84.20000
LogP -0.17
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.680

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV1720000
CAS REGISTRY NUMBER :
1165-39-5
BEILSTEIN REFERENCE NO. :
1299768
LAST UPDATED :
199806
DATA ITEMS CITED :
39
MOLECULAR FORMULA :
C17-H12-O7
MOLECULAR WEIGHT :
328.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14900 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - pleural effusion Liver - jaundice, other or unclassified Endocrine - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
785 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4100 ug/kg/22W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12 mg/kg/30W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24 mg/kg/20W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8 mg/kg/20W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5600 ug/kg/2W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
Sperm Morphology
TYPE OF TEST :
DNA adduct

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Primate - monkey Kidney
DOSE/DURATION :
2 mg/L
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 48,1647,1972 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 10,51,1976 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,245,1993 TOXICOLOGY REVIEW LLOYA2 Lloydia. (Cincinnati, OH) V.1-41, 1938-78. For publisher information, see JNPRDF. Volume(issue)/page/year: 38,21,1975 TOXICOLOGY REVIEW BAREA8 Bacteriological Reviews. (Washington, DC) V.1-41, 1937-77. Volume(issue)/page/year: 30,460,1966 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974 TOXICOLOGY REVIEW IJNDAN Indian Journal of Nutrition and Dietetics. (Sri Avinashilingam Home Science College for Women, Coimbatore 641 043, India) V.7- 1970- Volume(issue)/page/year: 8,85,1971
Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger
Hazard Statements H225-H304-H315-H319-H340-H350-H372
Precautionary Statements P201-P210-P301 + P310-P305 + P351 + P338-P308 + P313-P331
Personal Protective Equipment Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;T+: Very toxic;F: Flammable;Xn: Harmful;
Risk Phrases R45
Safety Phrases 53-28-36/37-45-62-26-16-7-36
RIDADR UN 3462 6
WGK Germany 3
RTECS LV1720000
Packaging Group I
Hazard Class 6.1(a)
1162-65-8 structure

1162-65-8

~%

1165-39-5 structure

1165-39-5

Literature: Mutation Research, , vol. 313, # 1 p. 25 - 38
Total: 1 Page

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title: CAS No. 1165-39-5 | Chemsrc address: https://m.chemsrc.com/en/baike/164971.html

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