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Product Name: 2,2',4,4',5,5'-HEXACHLOROBIPHENYL
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35065-27-1

35065-27-1 structure

35065-27-1 structure

Name: PCB-153
Chemical Name: 2,2',4,4',5,5'-hexachlorobiphenyl
CAS Number: 35065-27-1
Molecular Formula: C₁₂H₄Cl₆
Molecular Weight: 360.878
Catalog: analytical chemistry food safety Dioxins, polychlorinated biphenyls, furans
Create Date: 2018-11-28 12:56:42
Modify Date: 2026-07-01 15:20:33

Name	2,2',4,4',5,5'-hexachlorobiphenyl
Synonyms	2,2'4,4',5,5'-Hexachlorobiphenyl PCB NO 2,2',4,4',5,5'-heptachlorobiphenyl 245245PCB 2,2’,4,4’,5,5’-Hexachlorobiphenyl Solution in Hexane, 100μg/mL BZ NO PCB No 153 so 57542, 2,2',4,4',5,5'-Hexachlorobiphenyl (purity) 2,2',4,4',5,5'-hexachlorobiphenyl solution 2,2μ,4,4μ,5,5μ-Hexachlorobiphenyl, 2,2μ,4,4μ,5,5μ-PCB PCB153 in Octane 2,2’,4,4’,5,5’-hexachloro-bipheny 1,1'-BIPHENYL,2,2',4,4',5,5' 2,2',4,4',5,5'-PCB 1,1'-Biphenyl,2,2',4,4',5,5'-hexachloro L20015300IO PCB No. 153 10μg/mLin Isooctane 2,2’,4,4’,5,5’-hexachloro-1’-biphenyl 2,2μ,4,4μ,5,5μ-Hexachlorobiphenyl solution, 2,2μ,4,4μ,5,5μ-PCB PCB No. 153 10 PCB No 153 Solution 2,4,5,2',4',5'-Hexachlorobiphenyl PCB No. 153 100 μg/mLin Hexane 2,2μ,4,4μ,5,5μ-Hexachlorobiphenyl CB153 C20015300 PCB No 2,2’,4,4’,5,5’-hexachloro-1,1’-biphenyl 2,2,4,4,5,5-Hexachlorobiphenyl Standd PCB 153 2,2',4,4',5,5'-htachlorobiphenyl 2,2',3,3',5,6'-HEXACHLOROBIPHENYL HCBP CB-153 2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl PCB153 in Cyclohexane 2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl (9CI) Biphenyl, 2,2',4,4',5,5'-hexachloro 2,4,5,2’,4’,5’-hexachlorobiphenyl 2,2',4,4',5,5'-Hexachlorobiphenyl k153 PCB No. 153 10 μg/mL in Isooctane PCBCONGENER153 PCB No. 153 100 μg/mLin Isooctane 1,2,4-trichloro-5-(2,4,5-trichlorophenyl)benzene 2,2',4,4',5,5'-hexachloromobiphenyl BALLSCHMITER NO 2,2′,4,4′,5,5′-Hexachlorobiphenyl

Density	1.6±0.1 g/cm3
Boiling Point	396.2±37.0 °C at 760 mmHg
Melting Point	103-104ºC
Molecular Formula	C₁₂H₄Cl₆
Molecular Weight	360.878
Flash Point	193.2±23.9 °C
Exact Mass	357.844421
LogP	6.83
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.627
Storage condition	2-8°C
Stability	Thermally stable and resistant to both oxidation and biological degradation.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DV5350000

CHEMICAL NAME :: 1,1'-Biphenyl, 2,2',4,4',5,5'-hexachloro-

CAS REGISTRY NUMBER :: 35065-27-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C12-H4-Cl6

MOLECULAR WEIGHT :: 360.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg/30D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 322 mg/kg/13W-C

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg/3D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 960 mg/kg/4W-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Metabolism (Intermediary) - porphyrin including bile pigments

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 1470 mg/kg/21D-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3650 mg/kg/104W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 50 mg/kg

SEX/DURATION :: female 8-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 448 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 112 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 448 mg/kg

SEX/DURATION :: female 10-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - physical

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 120 mg/kg

SEX/DURATION :: female 1-6 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 78 mg/kg

SEX/DURATION :: female 5-21 day(s) after conception lactating female 22 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: female 13-21 day(s) after conception lactating female 24 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 271 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1080 mg/kg

SEX/DURATION :: female 45-62 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

TYPE OF TEST :: DNA adduct

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 36400 ug/kg/5D

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 27,99,1979

Symbol	GHS08, GHS09
Signal Word	Warning
Hazard Statements	H373-H410
Precautionary Statements	P273-P391-P501
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	F: Flammable;Xi: Irritant;N: Dangerous for the environment;Xn: Harmful;
Risk Phrases	R11
Safety Phrases	16-26-33-36-61-60-35-62-29-9
RIDADR	UN 2315
Packaging Group	II
Hazard Class	9
HS Code	2903999090

Precursor 7
108-86-1 95-94-3 7145-82-6 35065-29-3
636-30-6 120-82-1 15721-02-5
DownStream 10
35694-08-7 51207-31-9 92-52-4 92-51-3
771-98-2 827-52-1 2051-60-7 15862-07-4
33284-50-3 70362-47-9

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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