1261253-79-5
1261253-79-5 structure
- Name: AT-9010
- Chemical Name: AT-9010
- CAS Number: 1261253-79-5
- Molecular Formula: C11H17FN5O13P3
- Molecular Weight: 539.20
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2021-09-12 21:07:19
- Modify Date: 2024-01-09 08:55:05
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AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].
| Name | AT-9010 |
|---|
| Description | AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1]. |
|---|---|
| Related Catalog | |
| Target |
NiRAN[1] |
| In Vitro | Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1]. |
| References |
| Molecular Formula | C11H17FN5O13P3 |
|---|---|
| Molecular Weight | 539.20 |
| Hazard Codes | Xi |
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