1261253-79-5

1261253-79-5 structure
1261253-79-5 structure
  • Name: AT-9010
  • Chemical Name: AT-9010
  • CAS Number: 1261253-79-5
  • Molecular Formula: C11H17FN5O13P3
  • Molecular Weight: 539.20
  • Catalog: Signaling Pathways Anti-infection SARS-CoV
  • Create Date: 2021-09-12 21:07:19
  • Modify Date: 2025-09-01 14:51:13
  • AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].

Name AT-9010
Description AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].
Related Catalog
Target

NiRAN[1]

In Vitro Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References

[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

Molecular Formula C11H17FN5O13P3
Molecular Weight 539.20
Hazard Codes Xi
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