AT-9010

Modify Date: 2024-01-09 08:55:05

AT-9010 Structure
AT-9010 structure
Common Name AT-9010
CAS Number 1261253-79-5 Molecular Weight 539.20
Density N/A Boiling Point N/A
Molecular Formula C11H17FN5O13P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AT-9010


AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].

 Names

Name AT-9010

 AT-9010 Biological Activity

Description AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].
Related Catalog
Target

NiRAN[1]

In Vitro Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
References

[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

 Chemical & Physical Properties

Molecular Formula C11H17FN5O13P3
Molecular Weight 539.20

 Safety Information

Hazard Codes Xi
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