Top Suppliers:I want be here

1948229-21-7

1948229-21-7 structure
1948229-21-7 structure
  • Name: Eliapixant
  • Chemical Name: Eliapixant
  • CAS Number: 1948229-21-7
  • Molecular Formula: C22H21F3N4O3S
  • Molecular Weight: 478.49
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel P2X Receptor
  • Create Date: 2021-09-06 11:14:56
  • Modify Date: 2024-01-05 12:42:47
  • Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

Name Eliapixant
Description Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].
Related Catalog
Target

IC50: 8 nM (P2X3 receptor)[1]

In Vivo Eliapixant can be used for the research of coughs and diabetes complications[1].
References

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.

[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.

Density 1.360±0.06 g/cm3(Predicted)
Molecular Formula C22H21F3N4O3S
Molecular Weight 478.49
Storage condition -20°C
Hazard Codes Xn
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.