Eliapixant

Modify Date: 2024-01-05 12:42:47

Eliapixant Structure
Eliapixant structure
Common Name Eliapixant
CAS Number 1948229-21-7 Molecular Weight 478.49
Density 1.360±0.06 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C22H21F3N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Eliapixant


Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].

 Names

Name Eliapixant

 Eliapixant Biological Activity

Description Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough[1][2].
Related Catalog
Target

IC50: 8 nM (P2X3 receptor)[1]

In Vivo Eliapixant can be used for the research of coughs and diabetes complications[1].
References

[1]. Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.

[2]. Morice A, et, al. Eliapixant (BAY 1817080), a P2X3 receptor antagonist, in refractory chronic cough: a randomised, placebo-controlled, crossover phase 2a study. Eur Respir J. 2021 May 13;2004240.

 Chemical & Physical Properties

Density 1.360±0.06 g/cm3(Predicted)
Molecular Formula C22H21F3N4O3S
Molecular Weight 478.49
Storage condition -20°C

 Safety Information

Hazard Codes Xn