161511-45-1
161511-45-1 structure
- Name: SDZ 224-015
- Chemical Name: SDZ 224-015
- CAS Number: 161511-45-1
- Molecular Formula: C30H35Cl2N3O9
- Molecular Weight: 652.52
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2021-09-05 11:00:17
- Modify Date: 2024-01-10 10:39:35
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SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM)[1][2].
| Name | SDZ 224-015 |
|---|
| Description | SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM)[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | SDZ 224-015 (0.3-300 μg/kg) potently reduces carrageenin-induced paw oedema[2]. SDZ 224-015 (0.2-5 mg/kg, p.o.) displays analgesic activity in the Randall-Selitto yeast-inflamed paw pressure test, significant at a dose of 1 mg/kg[2]. |
| References |
| Molecular Formula | C30H35Cl2N3O9 |
|---|---|
| Molecular Weight | 652.52 |