Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cedirogant
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Cedirogant
Price: ￥850.0/100mg ￥1450.0/250mg ￥2900.0/1g ￥150.0/10ml
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2055496-11-0

2055496-11-0 structure

2055496-11-0 structure

Name: Cedirogant
Chemical Name: Cedirogant
CAS Number: 2055496-11-0
Molecular Formula: C₂₄H₂₀Cl₃F₃N₂O₃
Molecular Weight: 547.78
Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
Create Date: 2021-12-22 14:17:24
Modify Date: 2024-09-17 09:49:39
Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].

Name	Cedirogant

Description	Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> ROR Research Areas >> Inflammation/Immunology
Target	RORγt[1]
In Vitro	The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research[1].
References	[1]. Elena Campione, et al. Experimental Pharmacological Management of Psoriasis. J Exp Pharmacol. 2021 Jul 26;13:725-737. [2]. Christian Gege. Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently? Expert Opin Drug Discov. 2021 Jul 7;1-19.

Molecular Formula	C₂₄H₂₀Cl₃F₃N₂O₃
Molecular Weight	547.78

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