Cedirogant

Modify Date: 2024-09-17 09:49:39

Cedirogant Structure
Cedirogant structure
Common Name Cedirogant
CAS Number 2055496-11-0 Molecular Weight 547.78
Density N/A Boiling Point N/A
Molecular Formula C24H20Cl3F3N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cedirogant


Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].

 Names

Name Cedirogant

 Cedirogant Biological Activity

Description Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis research[1][2].
Related Catalog
Target

RORγt[1]

In Vitro The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research[1].
References

[1]. Elena Campione, et al. Experimental Pharmacological Management of Psoriasis. J Exp Pharmacol. 2021 Jul 26;13:725-737.

[2]. Christian Gege. Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently? Expert Opin Drug Discov. 2021 Jul 7;1-19.

 Chemical & Physical Properties

Molecular Formula C24H20Cl3F3N2O3
Molecular Weight 547.78
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