DC Chemicals Limited
China
Product Name: PARP/EZH2-IN-1
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

2687273-52-3

2687273-52-3 structure

2687273-52-3 structure

Name: PARP/EZH2-IN-1
Chemical Name: PARP/EZH2-IN-1
CAS Number: 2687273-52-3
Molecular Formula: C₄₃H₄₁FN₈O₅
Molecular Weight: 768.83
Catalog: Signaling Pathways Cell Cycle/DNA Damage PARP
Create Date: 2021-12-19 11:33:30
Modify Date: 2024-01-24 08:36:27
PARP/EZH2-IN-1 is a first-in-class dual PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM) inhibitor for triple-negative breast cancer with wild-type BRCA.

Name	PARP/EZH2-IN-1

Description	PARP/EZH2-IN-1 is a first-in-class dual PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM) inhibitor for triple-negative breast cancer with wild-type BRCA.
Related Catalog	Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Epigenetics >> Histone Methyltransferase Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	PARP-1:6.87 nM (IC50) EZH2:36.51 nM (IC50)
References	[1]. Wang C, et al. Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA. J Med Chem. 2021 Sep 9;64(17):12630-12650.

Molecular Formula	C₄₃H₄₁FN₈O₅
Molecular Weight	768.83