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PARP-1:6.87 nM (IC50)
EZH2:36.51 nM (IC50)
[1]. Wang C, et al. Discovery of First-in-Class Dual PARP and EZH2 Inhibitors for Triple-Negative Breast Cancer with Wild-Type BRCA. J Med Chem. 2021 Sep 9;64(17):12630-12650.