2369979-68-8
2369979-68-8 structure
- Name: JHU 37160
- Chemical Name: JHU37160
- CAS Number: 2369979-68-8
- Molecular Formula: C19H20ClFN4
- Molecular Weight: 358.8403
- Create Date: 2022-01-07 10:12:16
- Modify Date: 2024-07-07 13:04:23
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JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.
| Name | JHU37160 |
|---|---|
| Synonyms | MFCD20727945 |
| Description | JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue. |
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| Molecular Formula | C19H20ClFN4 |
|---|---|
| Molecular Weight | 358.8403 |