JHU 37160
Modify Date: 2024-07-07 13:04:23
JHU 37160 structure
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Common Name | JHU 37160 | ||
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| CAS Number | 2369979-68-8 | Molecular Weight | 358.8403 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H20ClFN4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JHU 37160JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue. |
| Name | JHU37160 |
|---|---|
| Synonym | More Synonyms |
| Description | JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue. |
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| Molecular Formula | C19H20ClFN4 |
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| Molecular Weight | 358.8403 |
| MFCD20727945 |