1103920-19-9

1103920-19-9 structure

Name: Anti-inflammatory agent 8
Chemical Name: Anti-inflammatory agent 8
CAS Number: 1103920-19-9
Molecular Formula: C₁₈H₁₅N₅OS₂
Molecular Weight: 381.47
Create Date: 2022-06-09 19:36:27
Modify Date: 2024-01-08 18:39:07
Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active[1].

Name	Anti-inflammatory agent 8

Description	Anti-inflammatory agent 8 (compound 13) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 8 expresses activity on COX-2 enzyme more than COX-1 with an IC50 of 0.09 nM. Anti-inflammatory agent 8 is orally active[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
References	[1]. Darwish SA, et al. New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies [published online ahead of print, 2022 Jan 29]. Bioorg Chem. 2022;120:105644.

Molecular Formula	C₁₈H₁₅N₅OS₂
Molecular Weight	381.47