2490589-09-6

2490589-09-6 structure

Name: sEH/AChE-IN-2
Chemical Name: sEH/AChE-IN-2
CAS Number: 2490589-09-6
Molecular Formula: C₃₀H₃₃ClF₃N₅O₃
Molecular Weight: 604.06
Create Date: 2022-05-19 16:41:42
Modify Date: 2025-08-26 22:42:41
sEH/AChE-IN-2 (Compound 12b) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-2 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-2 has the potential for the research of Alzheimer's disease (AD)[1].

Name	sEH/AChE-IN-2

Description	sEH/AChE-IN-2 (Compound 12b) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-2 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-2 has the potential for the research of Alzheimer's disease (AD)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Codony S, et al. Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease. J Med Chem. 2022;65(6):4909-4925.

Molecular Formula	C₃₀H₃₃ClF₃N₅O₃
Molecular Weight	604.06