2484811-39-2

2484811-39-2 structure

Name: ATX inhibitor 14
Chemical Name: ATX inhibitor 14
CAS Number: 2484811-39-2
Molecular Formula: C₂₆H₂₆Cl₂N₄O₃S
Molecular Weight: 545.48
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2022-07-17 19:25:36
Modify Date: 2024-01-12 12:08:58
ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research[1].

Name	ATX inhibitor 14

Description	ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
Target	Autotaxin:0.41 nM (IC50)
References	[1]. Hongrui Lei, et al. Structural and PK-guided identification of indole-based non-acidic autotaxin (ATX) inhibitors exhibiting high in vivo anti-fibrosis efficacy in rodent model. Eur J Med Chem. 2022 Jan 5;227:113951.

Molecular Formula	C₂₆H₂₆Cl₂N₄O₃S
Molecular Weight	545.48