ATX inhibitor 14

Modify Date: 2024-01-12 12:08:58

ATX inhibitor 14 Structure
ATX inhibitor 14 structure
Common Name ATX inhibitor 14
CAS Number 2484811-39-2 Molecular Weight 545.48
Density N/A Boiling Point N/A
Molecular Formula C26H26Cl2N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ATX inhibitor 14


ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research[1].

 Names

Name ATX inhibitor 14

 ATX inhibitor 14 Biological Activity

Description ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research[1].
Related Catalog
Target

Autotaxin:0.41 nM (IC50)

References

[1]. Hongrui Lei, et al. Structural and PK-guided identification of indole-based non-acidic autotaxin (ATX) inhibitors exhibiting high in vivo anti-fibrosis efficacy in rodent model. Eur J Med Chem. 2022 Jan 5;227:113951.

 Chemical & Physical Properties

Molecular Formula C26H26Cl2N4O3S
Molecular Weight 545.48
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