2715225-58-2

2715225-58-2 structure
2715225-58-2 structure
  • Name: Antimalarial agent 12
  • Chemical Name: Antimalarial agent 12
  • CAS Number: 2715225-58-2
  • Molecular Formula: C26H18BrClN2O2
  • Molecular Weight: 505.79
  • Catalog: Research Areas Infection
  • Create Date: 2022-07-01 19:59:34
  • Modify Date: 2024-04-06 14:59:59
  • Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli[1].

Name Antimalarial agent 12
Description Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli[1].
Related Catalog
References

[1]. Hanan Almolhim, et al. Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro. ACS Med Chem Lett. 2022 Feb 24;13(3):371-376.

Molecular Formula C26H18BrClN2O2
Molecular Weight 505.79