Antimalarial agent 12

Modify Date: 2025-08-27 23:29:02

Antimalarial agent 12 Structure
Antimalarial agent 12 structure
Common Name Antimalarial agent 12
CAS Number 2715225-58-2 Molecular Weight 505.79
Density N/A Boiling Point N/A
Molecular Formula C26H18BrClN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antimalarial agent 12


Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli[1].

 Names

Name Antimalarial agent 12

 Antimalarial agent 12 Biological Activity

Description Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli[1].
Related Catalog
References

[1]. Hanan Almolhim, et al. Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro. ACS Med Chem Lett. 2022 Feb 24;13(3):371-376.

 Chemical & Physical Properties

Molecular Formula C26H18BrClN2O2
Molecular Weight 505.79
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