2756099-59-7

2756099-59-7 structure

Name: Dual FAAH/sEH-IN-1
Chemical Name: Dual FAAH/sEH-IN-1
CAS Number: 2756099-59-7
Molecular Formula: C₂₅H₂₂ClN₃O₃S₂
Molecular Weight: 512.04
Catalog: Signaling Pathways Metabolic Enzyme/Protease FAAH
Create Date: 2022-06-29 11:17:12
Modify Date: 2024-01-02 20:21:19
Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].

Name	Dual FAAH/sEH-IN-1

Description	Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH Signaling Pathways >> Neuronal Signaling >> FAAH
Target	IC50: 9.6 nM (sEH) and 7 nM (FAAH)[1]
References	[1]. Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.

Molecular Formula	C₂₅H₂₂ClN₃O₃S₂
Molecular Weight	512.04