Dual FAAH/sEH-IN-1

Modify Date: 2024-01-02 20:21:19

Dual FAAH/sEH-IN-1 Structure
Dual FAAH/sEH-IN-1 structure
Common Name Dual FAAH/sEH-IN-1
CAS Number 2756099-59-7 Molecular Weight 512.04
Density N/A Boiling Point N/A
Molecular Formula C25H22ClN3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dual FAAH/sEH-IN-1


Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].

 Names

Name Dual FAAH/sEH-IN-1

 Dual FAAH/sEH-IN-1 Biological Activity

Description Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].
Related Catalog
Target

IC50: 9.6 nM (sEH) and 7 nM (FAAH)[1]

References

[1]. Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.

 Chemical & Physical Properties

Molecular Formula C25H22ClN3O3S2
Molecular Weight 512.04