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1627094-88-5

1627094-88-5 structure
1627094-88-5 structure
  • Name: Gü2602
  • Chemical Name: Gü2602
  • CAS Number: 1627094-88-5
  • Molecular Formula: C16H22N4O3
  • Molecular Weight: 318.37
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Cathepsin
  • Create Date: 2022-06-27 12:09:51
  • Modify Date: 2025-08-27 14:16:25
  • Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].

Name Gü2602
Description Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].
Related Catalog
Target

Ki: 0.013 nM (mCatK)[1]

References

[1]. Benýšek J, et al. Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem. 2022 Dec;37(1):515-526.

Molecular Formula C16H22N4O3
Molecular Weight 318.37
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