2582758-61-8

2582758-61-8 structure

Name: MIF-IN-6
Chemical Name: MIF-IN-6
CAS Number: 2582758-61-8
Molecular Formula: C₁₈H₁₃ClFN₅O₂
Molecular Weight: 385.78
Catalog: Research Areas Cancer
Create Date: 2022-06-26 12:56:25
Modify Date: 2024-01-10 20:10:13
MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].

Name	MIF-IN-6

Description	MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	IC50: 1.4 μM (MIF)[1] Ki: 0.96 μM (MIF)[1]
References	[1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

Molecular Formula	C₁₈H₁₃ClFN₅O₂
Molecular Weight	385.78