MIF-IN-6

Modify Date: 2024-01-10 20:10:13

MIF-IN-6 structure	Common Name	MIF-IN-6
	CAS Number	2582758-61-8	Molecular Weight	385.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₃ClFN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MIF-IN-6

MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].

Name	MIF-IN-6

Description	MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	IC50: 1.4 μM (MIF)[1] Ki: 0.96 μM (MIF)[1]
References	[1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849.

Molecular Formula	C₁₈H₁₃ClFN₅O₂
Molecular Weight	385.78

MIF-IN-6

Use of MIF-IN-6

Names

MIF-IN-6 Biological Activity

Chemical & Physical Properties