2541690-15-5

2541690-15-5 structure

Name: TGFβRI-IN-5
Chemical Name: TGFβRI-IN-5
CAS Number: 2541690-15-5
Molecular Formula: C₁₆H₁₂N₂O₆
Molecular Weight: 328.28
Catalog: Research Areas Cancer
Create Date: 2022-07-26 17:26:28
Modify Date: 2025-09-25 18:56:04
TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].

Name	TGFβRI-IN-5

Description	TGFβRI-IN-5 (Compound 4b) is a potent inhibitor of TGFβRI with an IC50 of 0.08 μM. TGFβRI-IN-5 displays amazing anticancer activity 5–7 times that of reference drug against all the tested cell lines. TGFβRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Ismail MMF, et al. Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors. Bioorg Chem. 2020;105:104368.

Molecular Formula	C₁₆H₁₂N₂O₆
Molecular Weight	328.28