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2396706-31-1

2396706-31-1 structure

2396706-31-1 structure

Name: GAK inhibitor 2
Chemical Name: GAK inhibitor 2
CAS Number: 2396706-31-1
Molecular Formula: C₂₀H₂₃N₃O₃S
Molecular Weight: 385.48
Catalog: Research Areas Infection
Create Date: 2022-08-16 17:52:49
Modify Date: 2024-01-15 18:17:31
GAK inhibitor 2 (Compound 14g) is a potent cyclin G-associated kinase (GAK) inhibitor with an IC50 of 0.024 μM. GAK inhibitor 2 shows antiviral activity with an EC50 of 1.049 μM against dengue virus (DENV)[1].

Name	GAK inhibitor 2

Description	GAK inhibitor 2 (Compound 14g) is a potent cyclin G-associated kinase (GAK) inhibitor with an IC50 of 0.024 μM. GAK inhibitor 2 shows antiviral activity with an EC50 of 1.049 μM against dengue virus (DENV)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IC50: 0.024 μM (GAK)[1]
References	[1]. Martinez-Gualda B, et al. Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase. Bioorg Med Chem. 2020 Jan 1;28(1):115188.

Molecular Formula	C₂₀H₂₃N₃O₃S
Molecular Weight	385.48

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