136966-86-4

136966-86-4 structure

Name: BChE-IN-12
Chemical Name: BChE-IN-12
CAS Number: 136966-86-4
Molecular Formula: C₃₁H₃₀O₅
Molecular Weight: 482.57
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-09-16 19:52:03
Modify Date: 2024-04-02 21:05:04
BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer's disease (AD)[1].

Name	BChE-IN-12

Description	BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer's disease (AD)[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	BChE:2.3 μM (IC50)
References	[1]. Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

Molecular Formula	C₃₁H₃₀O₅
Molecular Weight	482.57