493-95-8

493-95-8 structure

Name: savinin
Chemical Name: (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)oxolan-2-one
CAS Number: 493-95-8
Molecular Formula: C₂₀H₁₆O₆
Molecular Weight: 352.34
Catalog: Natural product Lignans
Create Date: 2018-02-27 08:00:00
Modify Date: 2024-01-11 05:43:07
Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].

Name	(3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)oxolan-2-one
Synonyms	savinin (3E,4R)-4-(1,3-Benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylene)dihydro-, (3E,4R)- (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)dihydrofuran-2(3H)-one hms2268a22

Description	Savinin is a lignan, whicn can serves as a valuable pharmacophore to exhibit anti-inflammatory effect[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Jung HJ, et al. Anticholinesterase and β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitory Compounds from the Heartwood of Juniperus chinensis. Chem Pharm Bull (Tokyo). 2015;63(11):955-60. [2]. Cho JY, et al. Savinin, a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation. Biol Pharm Bull. 2001 Feb;24(2):167-71.

Density	1.4±0.1 g/cm3
Boiling Point	573.5±39.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₆O₆
Molecular Weight	352.34
Flash Point	254.5±27.1 °C
Exact Mass	352.094696
PSA	63.22000
LogP	3.83
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.679

Hazard Codes	Xi

22554-63-8

~79%

493-95-8

Literature: Honda, Toshio; Kimura, Nobuaki; Sato, Shigeki; Kato, Daishiro; Tominaga, Hideo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 8 p. 1043 - 1046

2373-80-0

493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

2815-95-4

493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

17187-77-8

493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

161745-67-1

493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

196804-99-6

493-95-8

Literature: Charlton, James L.; Chee, Gaik-Lean Canadian Journal of Chemistry, 1997 , vol. 75, # 8 p. 1076 - 1083

Precursor 6
22554-63-8 2373-80-0 2815-95-4 17187-77-8
161745-67-1 196804-99-6
DownStream 0

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4