1202761-21-4

1202761-21-4 structure

1202761-21-4 structure

Name: Biotinyl-NH-PEG3-C3-amido-C3-COOH
Chemical Name: Biotinyl-NH-PEG3-C3-amido-C3-COOH
CAS Number: 1202761-21-4
Molecular Formula: C₂₅H₄₄N₄O₈S
Molecular Weight: 560.70
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2022-11-01 08:54:35
Modify Date: 2024-04-08 20:50:35
Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotinyl-NH-PEG3-C3-amido-C3-COOH

Description	Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₅H₄₄N₄O₈S
Molecular Weight	560.70