127663-77-8

127663-77-8 structure

127663-77-8 structure

Name: Ganglioside GM2
Chemical Name: Ganglioside GM2
CAS Number: 127663-77-8
Molecular Formula: C₆₇H₁₂₁N₃O₂₆
Molecular Weight: 1384.68
Catalog: Research Areas Cancer
Create Date: 2023-01-15 14:34:31
Modify Date: 2024-04-07 11:33:18
Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease[1][2].

Name	Ganglioside GM2

Description	Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Tai T, et al. Ganglioside GM2 as a human tumor antigen (OFA-I-1). Proc Natl Acad Sci U S A. 1983 Sep;80(17):5392-6. [2]. Anheuser S, et al. Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity. J Lipid Res. 2015 Sep;56(9):1747-61. [3]. Nakamura K, et al. Dissection and optimization of immune effector functions of humanized anti-ganglioside GM2 monoclonal antibody. Mol Immunol. 2000 Dec;37(17):1035-46.

Molecular Formula	C₆₇H₁₂₁N₃O₂₆
Molecular Weight	1384.68