Top Suppliers:I want be here

2642181-22-2

2642181-22-2 structure
2642181-22-2 structure
  • Name: TP0597850
  • Chemical Name: TP0597850
  • CAS Number: 2642181-22-2
  • Molecular Formula: C41H57N9O13S
  • Molecular Weight: 916.01
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
  • Create Date: 2023-04-06 20:36:20
  • Modify Date: 2024-04-05 17:51:59
  • TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1].

Name TP0597850
Description TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1].
Related Catalog
Target

MMP2:0.22 nM (IC50)

MMP-12:250 nM (IC50)

MMP13:240 nM (IC50)

In Vitro TP0597850 (化合物 18) 在广谱 pH 值下表现出极高的化学稳定性[1]。 TP0597850 的抑制常数 Ki 值为 0.034 nM[1]。
References

[1]. Takeuchi T, et al. Discovery of TP0597850: A Selective, Chemically Stable, and Slow Tight-Binding Matrix Metalloproteinase-2 Inhibitor with a Phenylbenzamide-Pentapeptide Hybrid Scaffold. J Med Chem. 2023 Jan 12;66(1):822-836.  

Molecular Formula C41H57N9O13S
Molecular Weight 916.01
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.