1264748-47-1

1264748-47-1 structure

Name: WH-15
Chemical Name: WH-15
CAS Number: 1264748-47-1
Molecular Formula: C₃₁H₄₃N₂O₁₈P₃
Molecular Weight: 824.60
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
Create Date: 2023-04-06 15:00:56
Modify Date: 2026-07-08 15:19:56
WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells[1].

Name	WH-15
Synonyms	D-myo-Inositol, 4,5-bis(dihydrogen phosphate) 1-[2-(octyloxy)-4-[[[(6-quinolinylamino)carbonyl]oxy]methyl]phenyl hydrogen phosphate]

Description	WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Neurological Disease
References	[1]. Huang W, et al. A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes. ACS Chem Biol. 2011 Mar 18;6(3):223-8.

Molecular Formula	C₃₁H₄₃N₂O₁₈P₃
Molecular Weight	824.60