115473-56-8

115473-56-8 structure

Name: L-Glutamic acid-13C2
Chemical Name: L-Glutamic acid-13C2
CAS Number: 115473-56-8
Molecular Formula: C₃₁₃C₂H₉NO₄
Molecular Weight: 149.11
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-04-21 00:04:19
Modify Date: 2024-01-16 17:13:26
L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].

Name	L-Glutamic acid-13C2

Description	L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Apoptosis >> Ferroptosis Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.

Molecular Formula	C₃₁₃C₂H₉NO₄
Molecular Weight	149.11