L-Glutamic acid-13C2

Modify Date: 2024-01-16 17:13:26

L-Glutamic acid-13C2 Structure
L-Glutamic acid-13C2 structure
Common Name L-Glutamic acid-13C2
CAS Number 115473-56-8 Molecular Weight 149.11
Density N/A Boiling Point N/A
Molecular Formula C313C2H9NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Glutamic acid-13C2


L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].

 Names

Name L-Glutamic acid-13C2

 L-Glutamic acid-13C2 Biological Activity

Description L-Glutamic acid-13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.  

 Chemical & Physical Properties

Molecular Formula C313C2H9NO4
Molecular Weight 149.11