2629192-96-5

2629192-96-5 structure

Name: LRRK2/NUAK1/TYK2-IN-1
Chemical Name: LRRK2/NUAK1/TYK2-IN-1
CAS Number: 2629192-96-5
Molecular Formula: C₂₀H₁₁F₃N₆
Molecular Weight: 392.34
Catalog: Signaling Pathways Autophagy LRRK2
Create Date: 2023-04-21 12:00:15
Modify Date: 2025-09-05 07:06:16
LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].

Name	LRRK2/NUAK1/TYK2-IN-1

Description	LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Inflammation/Immunology Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
Target	Tyk2 NUAK1
References	[1]. Roland Koestler, et al. 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as lrrk2, nuak1 and/or tyk2 kinase modulators for the treatment of e.g. autoimmune disease. Patent WO2021048618A1.

Molecular Formula	C₂₀H₁₁F₃N₆
Molecular Weight	392.34