106-25-2

106-25-2 structure

Name: cis-3,7-Dimethyl-2,6-octadien-1-ol
Chemical Name: nerol
CAS Number: 106-25-2
Molecular Formula: C₁₀H₁₈O
Molecular Weight: 154.249
Catalog: Flavors and spices Synthetic spice Alcoholic spice Terpene alcohol
Create Date: 2018-02-04 08:00:00
Modify Date: 2024-01-01 22:45:46
Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2].

Name	nerol
Synonyms	2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)- Nerol NEROL BJ 2,6-Octadien-1-ol,3,7-dimethyl-, (2Z)- (Z)-3,7-Dimethylocta-2,6-dien-1-ol NEROLEX cis-2,6-Dimethyl-2,6-octadien-8-ol FEMA 2770 (2Z)-3,7-Dimethyl-2,6-octadien-1-ol Vernol EINECS 203-378-7 NEROL 70 NERYL ALCOHOL cis-3,7-Dimethyl-2,6-octadien-1-ol MFCD00063204 Neraniol 2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)- cis-3,7-Dimethyl-2,6-octadien-1-ol,Nerol (Z)-Nerol (2Z)-3,7-Dimethylocta-2,6-dien-1-ol

Description	Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Nerol induces apoptosis associated with the generation of ROS and Ca2+ overload in saprotrophic fungus Aspergillus flavus[1]. The antifungal activity of Nerol (NEL) against Candida albicans, a pathogenic fungus, has a minimum inhibitory concentration (MIC) of 4.4μM that causes noteworthy candidacidal activity through an apoptosis-like mechanism[2]. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS in Candida albicans[2].
References	[1]. Tian J, et al. Nerol-induced apoptosis associated with the generation of ROS and Ca²⁺ overload in saprotrophic fungus Aspergillus flavus. Appl Microbiol Biotechnol. 2018 Aug;102(15):6659-6672. [2]. Tian J, et al. Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca²⁺ and ROS in Candida albicans. Int J Biochem Cell Biol. 2017 Apr;85:114-122.

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976 ** ACUTE TOXICITY DATA **

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 21,342,1962

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,623,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9625 No. of Facilities: 1991 (estimated) No. of Industries: 4 No. of Occupations: 9 No. of Employees: 13881 (estimated) No. of Female Employees: 7957 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	RG5840000
HS Code	2907299090

HS Code	2905221000
Summary	2905221000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%