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2698389-43-2

2698389-43-2 structure

2698389-43-2 structure

Name: JAK kinase-IN-1
Chemical Name: JAK kinase-IN-1
CAS Number: 2698389-43-2
Molecular Formula: C₁₇H₁₉F₂N₇OS
Molecular Weight: 407.44
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2023-10-03 17:14:18
Modify Date: 2025-09-17 23:06:08
JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1].

Name	JAK kinase-IN-1

Description	JAK kinase-IN-1 (Example 1) is a JAK inhibitor. JAK kinase-IN-1 inhibits TYK2, JAK1, JAK2 and JAK3 with IC50 values of 4.2 nM, 32 nM, 27 nM, 3473 nM respectively[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
References	[1]. Yao, Yuanshan, et al. Preparation of (pyrimidinyl)thiadiazabicyclo[3.2.1]octane derivatives as JAK kinase inhibitor and used for preventing and/or treating diseases or disorders related to JAK kinase activity or expression. Patent. WO2021180143.

Molecular Formula	C₁₇H₁₉F₂N₇OS
Molecular Weight	407.44

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