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2925583-17-9

2925583-17-9 structure

2925583-17-9 structure

Name: MDM2/XIAP-IN-3
Chemical Name: MDM2/XIAP-IN-3
CAS Number: 2925583-17-9
Molecular Formula: C₂₉H₃₀N₂O₅S
Molecular Weight: 518.62
Catalog: Signaling Pathways Apoptosis IAP
Create Date: 2023-09-19 22:26:52
Modify Date: 2026-11-01 17:24:00
MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].

Name	MDM2/XIAP-IN-3
Synonyms	Furo[3,2-c]quinoline-8-sulfonamide, N-(3-acetylphenyl)-2,3,3a,4,5,9b-hexahydro-4-[4-(2-methyl-1-oxopropyl)phenyl]

Description	MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> MDM-2/p53 Signaling Pathways >> Apoptosis >> IAP
References	[1]. Albadari N, et al. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. Eur J Med Chem. 2023 Jul 5;255:115423.

Molecular Formula	C₂₉H₃₀N₂O₅S
Molecular Weight	518.62

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