2669726-78-5

2669726-78-5 structure

Name: URAT1&XO inhibitor 1
Chemical Name: URAT1&XO inhibitor 1
CAS Number: 2669726-78-5
Molecular Formula: C₂₀H₁₃N₅O₃S
Molecular Weight: 403.41
Catalog: Signaling Pathways Membrane Transporter/Ion Channel URAT1
Create Date: 2023-10-09 13:21:51
Modify Date: 2025-08-24 19:37:53
URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].

Name	URAT1&XO inhibitor 1

Description	URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> URAT1 Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase
References	[1]. Fengwei Lin, et al. Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase. European Journal of Medicinal Chemistry. Volume 257, 5 September 2023, 115532.

Molecular Formula	C₂₀H₁₃N₅O₃S
Molecular Weight	403.41