URAT1&XO inhibitor 1

Modify Date: 2025-08-24 19:37:53

URAT1&XO inhibitor 1 Structure
URAT1&XO inhibitor 1 structure
Common Name URAT1&XO inhibitor 1
CAS Number 2669726-78-5 Molecular Weight 403.41
Density N/A Boiling Point N/A
Molecular Formula C20H13N5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of URAT1&XO inhibitor 1


URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].

 Names

Name URAT1&XO inhibitor 1

 URAT1&XO inhibitor 1 Biological Activity

Description URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research[1].
Related Catalog
References

[1]. Fengwei Lin, et al. Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase. European Journal of Medicinal Chemistry. Volume 257, 5 September 2023, 115532.

 Chemical & Physical Properties

Molecular Formula C20H13N5O3S
Molecular Weight 403.41
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.